ECOLOGY/EVOLUTION: Regulating Food Intake

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Regulating food intake.

EVERY ORGANISM INGESTS FOOD (energy). If it takes in too little, it will starve; if it takes in too much, it will become obese. Too little is readily defined as caloric intake less than expenditure, and too much is simply the opposite. Multiple regulatory pathways are known that promote and inhibit feeding and thus regulate energy balance. However, these pathways and their interactions remain i...

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Afferent signals regulating food intake.

Food intake is a regulated system. Afferent signals provide information to the central nervous system, which is the centre for the control of satiety or food seeking. Such signals can begin even before food is ingested through visual, auditory and olfactory stimuli. One of the recent interesting findings is the demonstration that there are selective fatty acid taste receptors on the tongue of r...

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Neural and hormonal mechanisms regulating food intake.

In this outline of the neural control of food intake, no attempt has been made to provide a comprehensive survey of the literature since there are several symposia and reviews available which summarize the extensive work in this field (Grossman, 1975; Novin et al. 1976; Silverstone, 1976; Morgane & Panksepp, 1980; Hoebel & Novin, 1982). Instead some current concepts of the neural control of foo...

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Ghrelin: a hormone regulating food intake and energy homeostasis.

Regulation of energy homeostasis requires precise coordination between peripheral nutrient-sensing molecules and central regulatory networks. Ghrelin is a twenty-eight-amino acid orexigenic peptide acylated at the serine 3 position mainly with an n-octanoic acid, which is produced mainly in the stomach. It is the endogenous ligand of the growth hormone secretagogue (GHS) receptors. Since plasma...

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The effects of morphine and nicotine co-administration on body weight, food intake and appetite-regulating peptides in rats

Previous studies in humans and animals have reported that nicotine administration decreases body weightand caloric intake. Opiate and cigarette have been used concomitantly as drug abuse. The aim of the present study was, therefore, to analyze the effect of chronic co-administration of nicotine and morphine on food intake, body weight and on some feeding-associated peptides. All experiments wer...

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ژورنال

عنوان ژورنال: Science

سال: 2006

ISSN: 0036-8075,1095-9203

DOI: 10.1126/science.311.5761.579a